- Homepage
- Departments
- Research Safety & Services
- Animal Research Safety
- Chemicals and Novel Compounds in Animals
Chemicals and Novel Compounds in Animals
- Pest Management
- Fire Plan Review and Inspection
- Building Codes Enforcement
- Chartfield Form Codes Permits
- Temporary Structures on Campus – Including Tents
- Plan Submittal Guidelines
- Permit Instructions
- Permit Application Process
- Inspections
- Code Permit Fee Schedule
- Applicable Building Codes for the State of Florida and the University of Florida
- Certificate of Occupancy or Completion
- ADA Assessment
- Building Emergency Coordinators
- Risk Management Insurance & Liability
- Occupational Medicine
- Industrial Hygiene & Occupational Safety
- Ergonomics
- Drones/UAS
- Boating & Dive Safety
- Report Lab Closeout
- Radiation and Laser Safety
- Hazardous Waste Management
- Gator TRACS
- Chemical and Lab Safety
- Chemical Safety Information
- Signage
- Standard Operating Procedures
- Signage & Stickers
- Safety Surveys
- Peroxide Forming Compounds
- New Labs, Moving Labs & Closeouts
- Minors and Visitors in the Lab
- Lessons Learned
- Lab Ventilation & Fume Hoods
- Lab Safety Manual
- Hydrofluoric Acid
- First Aid Kit Info
- Equipment Purchase Approval
- Equipment Decontamination
- Cryogens
- Controlled Substances & Pharmaceutical Products
- Compressed Gas
- Chemical Storage and Management
- Chemical Spills
- Chemical Inventory
- Chemical Hygiene Plan
- Chemical Exposures
- Acids That Deserve Special Attention
- Biological Safety
- Vaccination for Research Personnel
- Shipping and Transport of Biological Materials
- Select Agents
- SARS-CoV-2/COVID-19 Specimen Research
- Research Involving Flying Insects
- Recombinant & Synthetic Nucleic Acids
- Plant Research & Greenhouses
- NIH Guidelines Flowchart
- BloodBorne Pathogen Program
- BioPath Program
- Biological Spills
- Biohazardous Waste Disposal
- Biohazard Project Registration
- Autoclaves
- Acute Biological Toxins
- Animal Research Safety
The University of Florida requires the Chemical Hygiene Program for all UF employees and affiliates (students, volunteers, contractors, etc.) who work with chemicals in laboratory settings, including animal research areas.
- It is the responsibility of the investigator to notify research personnel and ACS staff of any hazards and SOPs required to handle animals exposed to chemical hazards.
- Investigators are required to report the use of chemical hazards in animals in their IACUC protocol.
- During the protocol development/review phase, a risk assessment of each chemical hazard is conducted by the research staff, EH&S, IACUC, and the ACS veterinary staff.
- When working with chemicals, occupational health risks for both research and animal care staff arise from:
- Toxicity, half-life and metabolic byproducts of the compound
- Methods of preparation
- Concentration and method of administration
- Amount of material excreted
- Chemical Hazards: Follow the EH&S Guidelines for SOPs to create a Chemicals in Animals SOP using the manufacturer’s SDS and literature. This is used to complete your IACUC Protocol.
- Novel Compounds: the following information should be addressed within the IACUC Protocol and SOP:
- Description of the parent, or closely related compound(s).
- Current toxicity and pharmacokinetic data, if available.
- List of Common Chemical Hazards
SOP template and examples
- ChemicalsInAnimals SOP
- ExampleSOP_CCl4 in Animals
- ExampleSOP_Chemotherapeutics in Animals
- Chemical SOP Example_Fixatives
- ExampleSOP_Nicotine in Animals
- ExampleSOP_Novel Compounds in Animals
- ExampleSOP_Tamoxifen Food in Animals
- ExampleSOP_Tamoxifen Injections in Animals