FDA-Licensed Vaccines that may be Recommended


General Indications and ACIP Guidance for Use

Tetanus*, Diphtheria, and Pertussis (Tdap) Vaccine

UF Environmental Health and Safety strongly recommends TDaP vaccination for individuals who work directly with tetanus, diphtheria or pertussis toxins and/or toxin-producing strains of Clostridium tetani, Corynebacterium diphtheria, or Bordetella pertussis.

The CDC/NIH’s Biosafety in Microbiological and Biomedical Laboratories recommends vaccination for work with Corynebacterium diphtheria and Clostridium tetani and tetanus toxin noting that while the risk of laboratory-associated tetanus and diphtheria is low, the administration of an adult diphtheria-tetanus toxoid at 10-year intervals further reduces the risk to laboratory and animal care workers and is therefore strongly recommended.  Note: at the time of publishing of the BMBL 5th edition, the pertussis vaccine was not yet licensed for use in adults.  As of 2010, ACIP now recommends that all adults aged 19-64 years should receive a single dose of the Tdap vaccine (who have not already received a dose of Tdap) to replace a single dose of Td vaccine.

Human papillomavirus (HPV) Vaccine

9-valent HPV Vaccine (9vHPV; GARDASIL®9)

  • As per ACIP recommendations, two doses are recommended for males and females who initiate the vaccine series at 9-14 years of age.
  • Three doses remain recommended for persons who initiate the vaccination series at ages 15 through 26 years and for immunocompromised persons.

Influenza Vaccine**

Per NIH guidelines, the influenza vaccines may be recommended for work with circulating human influenza strains (e.g., H1/H3/B) and low pathogenicity avian influenza (LPAI) strains (e.g., H1-4, H6, H8-16), and equine and swine influenza viruses and other RG2 influenza viruses work with at the BSL-2/ABSL-2 level.  In addition, UF strongly encourages influenza vaccination for all individuals working in a BSL-3 high containment laboratory since many of the biological agents worked with at this level cause flu-like symptoms.

Pneumococcal Vaccine

Vaccination may be indicated/recommended by the ACIP for adults ≥19 years based on underlying medical conditions including persons who may be at increased risk for invasive pneumococcal disease (IPD) including, but not limited to,  persons with diabetes mellitus, asthma and cigarette smokers.  A complete list of vaccine recommendations by risk group can be found on the CDC website.

Varicella (chickenpox) Vaccine

ACIP recommends that all adults should be assessed for varicella immunity, and those who do not have evidence of immunity should receive 2 doses of single-antigen varicella vaccine 4-8 weeks apart.

Hepatitis B Vaccine

ACIP recommends vaccination for all personnel whose work-related activities involve exposure to blood or other potentially infectious body fluids in a health-care, laboratory, public safety or institutional setting.  In accordance with the Occupational Safety and Health Administration’s (OSHA) Bloodborne Pathogen Standard, personnel can decline the Hepatitis B vaccine but must sign the statement in Appendix A of the Standard.  Please use the “UF Bloodborne Pathogen Program Training and Vaccination Form Acceptance/Declination Statement” Form to document acceptance/declination of the Hepatitis B vaccine.

* Note: The Tetanus Vaccine is required for ALL personnel with animal contact.

**Note: The seasonal Influenza Vaccine is required for all personnel working with RG3 influenza viruses. In accordance with UF Health Shands Medical Staff Policy, all UF Health Shands Medical Staff and Allied Health Staff including researchers and volunteers supporting human-patient care programs are required to receive the seasonal Influenza vaccine.

Revised 2/7/2018