Toxin Table
Toxin |
Species |
Route |
LD50 |
Abrin |
Mouse |
IV |
0.7 |
Aerolysin |
Mouse |
IV |
7* |
Boutlinum Toxin A |
Mouse |
IP |
0.0012* |
Botulinum Toxin B |
Mouse |
IP |
0.0012* |
Botulinum Toxin C1 |
Mouse |
IV |
0.0011 |
Botulinum Toxin C2 |
Mouse |
IP |
0.0012 |
Botulinum Toxin D |
Mouse |
IP |
0.0004 |
Botulinum Toxin E |
Mouse |
|
0.0011* |
Botulinum Toxin F |
Mouse |
IV |
0.0025 |
Β-Bungarotoxin |
Mouse |
IP |
7.8 |
Caeruleotoxin |
Mouse |
IV |
40 |
Cereolysin |
Mouse |
IV |
40–80 |
Ciguatoxin 2 |
Mouse |
IP |
1 |
Ciguatoxin 3 |
Mouse |
IP |
0.9 |
Clostridium difficile enterotoxin A |
Mouse |
IP |
0.5 |
Clostridium perfringens alpha toxin, lecithinase |
Mouse |
IV |
3 |
Clostridium perfringens theta toxin, perfringolysin O |
Mouse |
IV |
13-16 |
Clostridium perfringens enterotoxin |
Mouse |
IV |
81 |
Clostridium perfringens beta-toxin |
Mouse |
IP |
4.5 |
Clostridium perfringens delta-toxin |
Mouse |
IV |
5* |
Clostridium perfringens epsilon-toxin |
Mouse |
|
0.1* |
Conotoxins |
|
|
10-100 |
Crotoxin |
Mouse |
IV |
82 |
Diacetoxyscirpenol (DAS)# |
Dog |
IV |
1100 |
Diphtheria toxin |
Mouse |
IV |
0.01 |
Listeriolysin |
Mouse |
|
3-12* |
Maitotoxin |
Mouse |
IP |
0.6 |
Modeccin |
Rat |
IP |
1.3 |
Nematocyst toxins |
Mouse |
IV |
33-70 |
Notexin |
Mouse |
IV |
5 |
Palytoxin |
Rat |
IV |
0.089 |
Pertussis toxin |
Mouse |
IP |
18 |
Pneumolysin |
Rabbit |
IV |
1.5 |
Pseudomonas aeruginosa exotoxin A |
Mouse |
IP |
14 |
Ricin |
Mouse |
IV |
2.2 |
Saxitoxin |
Mouse |
IV |
3-9 |
Scaritoxin |
Mouse |
IP |
50 |
Shiga toxin |
Mouse |
IP |
0.25 |
Shigella dysenteriae neurotoxin |
Mouse |
IP |
1.3 |
Streptolysin O |
Mouse |
IV |
8 |
Streptolysin S |
Mouse |
IV |
25 |
Staphylococcus aureus alpha toxin |
Mouse |
IV |
0.04-0.06 |
Staphylococcus aureus enterotoxin B |
Monkey |
IV |
20 |
Staphylococcus aureus enterotoxin F |
Rabbit |
SubQ |
2 |
T-2 toxin# |
Pig |
IV |
1000 |
Taipoxin |
Mouse |
IV |
2 |
Tetanus toxin |
Mouse |
SubQ |
0.003 |
Tetrodotoxin |
Mouse |
IV/IP |
8 |
Viscumin |
Mouse |
IV |
2.4 |
Volkensin |
Mouse |
IP |
1.38 |
Yersinia pestis murine toxin |
Mouse |
IV |
10 |
IV = intravenous; IP = intraperitoneal; SubQ = subcutaneous
Toxins in bold are Select Agent toxins.
#Although DAS and T-2 toxins have LD50 values > 100µg/kg body weight, they must be registered as Acute Toxins with the Biosafety Office due to the fact that they are Select Agent toxins.
*MLD = minimum lethal dose; lowest dose reported to kill at least one subject