FDA-Licensed Vaccines that may be Recommended


Vaccine General Indications and ACIP Guidance for Use

Tetanus*, Diptheria, and Pertussis (Tdap) Vaccine

UF Environmental Health and Safety strongly recommends TDaP vaccination for individuals who work directly with tetanus, diphtheria or pertussis toxins and/or toxin-producing strains of Clostridium tetani, Cornyebacterium diptheriae, or Bordetella pertussis.

The CDC/NIH’s Biosafety in Microbiological and Biomedical Laboratories recommends vaccination for work with Cornyebacterium diptheriae and Clostridium tetani and tetanus toxin noting that while the risk of laboratory-associated tetanus and diptheria is low, the administration of an adult diphtheria-tetanus toxoid at 10-year intervals further reduces the risk to laboratory and animal care and is therefore strongly recommended. Note: at the time of publishing of the BMBL 5th edition, the pertussis vaccine was not yet licensed for use in adults. As of 2010, ACIP now recommends that all adults aged 19-64 years should receive a single dose to the Tdap vaccine (who have not already received a dose of Tdap) to replace a single dose of Td vaccine).

Human papillomavirus (HPV) Vaccine

Quadrivalent HPV Vaccine (GARDASILTM)

  • Recommended for females aged 13-26 years who have not been previously vaccinated or who have not completed the full series.
  • Recommended for males aged 13-21 years who have not been vaccinated previously or who have not completed the 3-dose series; males aged 22 through 26 years may be vaccinated

Bivalent HPV Vaccine (Cervarix)

  • Recommended for females aged 13 through 26 years who have not been vaccinated previously or who have not completed the 3-dose series.
  • Not currently licensed for use in males.
Influenza vaccine** Per CDC/NIH guidance, the influenza vaccine may be recommended for work with circulating human influenza strains (e.g., H1/H3/B) and low pathogenicity avian influenza (LPAI) strains (e.g., H1-4, H6, H8-16), and equine and swine influenza viruses and other RG2 influenza viruses work with at the BSL-2/ABSL-2 level. In addition, UF strongly encourages influenza vaccination for all individuals working in a BSL-3 high containment laboratory since many of the biological agents worked with at this level cause flu-like symptoms.
Pneumococcal Vaccine Vaccination may be indicated/recommended for adults ≥19 years based on underlying medical conditions including persons who may be at increased risk for invasive pneumococcal disease (IPD) including, but not limited to, persons with diabetes mellitus, asthma and cigarette smokers. A complete list of vaccine recommendations by risk group can be found on the CDC website.
Varicella (chickenpox) Vaccine ACIP recommends that all adults should be assessed for varicella immunity, and those who do not have evidence of immunity should receive 2 doses of single-antigen varicella vaccine 4-8 weeks apart.
Hepatitis B Vaccine ACIP recommends vaccination for all personnel whose work-related activities involve exposure to blood or other potentially infectious body fluids in a health-care, laboratory, public safety or institutional setting. In accordance with the Occupational Safety and Health Administration’s (OSHA) Bloodborne Pathogen Standard, personnel can decline the Hepatitis B vaccine but must sign the statement in Appendix A of the Standard. Please use the UF Bloodborne Pathogen Program Training and Vaccination Form Acceptance/Declination Statement Form to document acceptance/declination of the Hepatitis B vaccine.

* Note: The Tetanus Vaccine is required for ALL personnel with animal contact (see ACIP Recommended/UF Required FDA-Licensed Vaccines).
**Note: The seasonal Influenza Vaccine is required for all personnel working with RG3 influenza viruses (see ACIP Recommended/UF Required FDA-Licensed Vaccines).

Original February 17, 2014